产品编号:B318150
产品规格:25g
产品价格:面议
| 标准品编号: | B318150 |
| 名称: | Berberine Hydrochloride |
| 别名: | 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium Chloride; Berberine Chloride; 7,8,13,13a-Tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)berbinium Chloride; Berberine Hydrochloride; NSC 646666; |
| CAS号: | 633-65-8 |
| 备用CAS: | Free Base: 2086-83-1 |
| 分子式: | C₂₀H₁₈ClNO₄ |
| 外观: | Pale Yellow to Yellow Solid |
| 熔点: | >160°C (dec.) |
| 分子量: | 371.84 |
| 储存: | 冰箱保存 |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs. |
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