产品编号：B288790

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	B288790
名称:	(E)-5-(4-(2-(Benzyl(pyridin-2-yl)amino)ethoxy)benzylidene)thiazolidine-2,4-dione
分子式:	C₂₄H₂₁N₃O₃S
分子量:	431.51
类别:	Building Blocks; Miscellaneous;
应用:	(E)-5-(4-(2-(benzyl(pyridin-2-yl)amino)ethoxy)benzylidene)thiazolidine-2,4-dione is an intermediate in the synthesis of N-Desmethyl Rosiglitazone (D292165), a metabolite of Rosiglitazone (R693500), an insulin sensitizer; binds to peroxisome proliferator activated receptor gamma (PPAR- γ).
文献	Balton, G.C., et al.: Xenobiotica, 26, 6, 627 (1996); Kim, K., et al.: J. Clin. Pharmacol., 45, 941 (2005); Kirchheiner, J., et al.: Clin. Pharmacol. Ther., 80, 657 (2006); O'Maille, G., et al.: J. Pharm. Biomed. Anal., 48, 934 (2008); Cantello, B.C.C., et al.: J. Med. Chem., 37, 3977 (1994); Oakes, N.D., et al.: Diabetes, 43, 1203 (1994); Balton, G.C., et al.: Xenobiotica, 26, 627 (1996), Barman, J.A., et al.: Drugs, 57, 921 (1999)