产品编号：B285725
产品规格：5mg
产品价格：面议
| 标准品编号: | B285725 |
| 名称: | 4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione |
| 别名: | GSK-3ß Inhibitor I, TDZD-8 |
| CAS号: | 327036-89-5 |
| 分子式: | C₁₀H₁₀N₂O₂S |
| 外观： | 白色固体 |
| 熔点: | 60-61°C |
| 分子量: | 222.26 |
| 储存: | -20°C Freezer |
| 溶解度: | Hexane |
| 类别: | Research Tools; Enzyme Activators and Inhibitors; |
| 应用: | Glycogen Synthase Kinase-3ß is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. TDZD-8 is a thiadiazolidinone (TDZD) analogue that acts as a highly selective, non-ATP competitive inhibitor of GSK-3ß ( IC50 =2nM). Binds to the active site of GSK-3ß. Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, PKA, and PKC (IC50 >100nM). |
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