产品编号：B279770

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	B279770
名称:	1-Benzyl 6-Ethyl 2-Acetyl-3-oxohexanedioate
分子式:	C₁₇H₂₀O₆
外观：	Oil
分子量:	320.34
溶解度:	Methanol, DCM, Ethyl Acetate
类别:	Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1-Benzyl 6-Ethyl 2-Acetyl-3-oxohexanedioate is an intermediate formed in the synthesis of Succinylacetone (S692060), a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. It was developed a stable-isotope for the determination of SA in dried blood spots (DBS) and liquid urine using a 13C4-SA as internal standard. The method was applied retrospectively and prospectively for the diagnosis of hepatorenal tyrosinemia and for follow-up of patients under treatment.
文献	Kvittingen, E., et al.: Inher. Metab. Dis., 14, 554 (1991); Lindstedt, S., et al.: Lancet, 340, 813 (1992); Schulze, A., et al.: Clin. Chem., 47, 1424 (2001); Allard, P., et al.: Clin. Biochem., 37, 1010 (2004)