产品编号：B261990

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	B261990
名称:	(R)-Benzyl 3-Methyl-2-(N-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)butanoate
分子式:	C₅₀H₄₉N₅O₃
外观：	Yellow Oil
分子量:	767.96
溶解度:	Dichloromethane; Ethyl Acetate; Methanol
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(R)-Benzyl 3-Methyl-2-(N-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)butanoate is an intermediate in the synthesis of ent-Valsartan (Valsartan USP Related Compound A) (V095755), which is the (R)-enantiomer of Valsartan (V095750), which is a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
文献	Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994); Corea, L., et al.: Clin. Pharmacol. Ther., 60, 341 (1996), Satana, E;., et al.: J. Pharm. Biomed. Anal., 25, 1009 (2001), Sironi, L., et al.: Hypertension, 37, 961 (2001),