产品编号：B208380

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	B208380
名称:	[3aR,4R(1E,3S),5R,6aS]-5-Benzoyloxy-4-(3-hydroxy-4-phenoxy-1-buten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one
别名:	(3aR,4R,5R,6aS)-5-(Benzoyloxy)-4-[(1E,3S)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]hexahydro-2H-cyclopenta[b]furan-2-one
CAS号:	208111-89-1
分子式:	C₂₄H₂₃ClO₆
分子量:	442.89
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	[3aR,4R(1E,3S),5R,6aS]-5-Benzoyloxy-4-(3-hydroxy-4-phenoxy-1-buten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one can be used as reagent/reactant in preparation of 15-Fluoro prostaglandin FP agonists as a new class of topical ocular hypotensives for the treatment of glaucoma. It can be obtained from (-)-Corey Lactone Benzoate (C694990) which a corey lactone derivative used in the preparation prostaglandin analogues for use as vasolidator as well as EP4 receptor agonists.
文献	Andersen, N.H. et al.: Prostaglandins, 22, 809 (1981); Klimko, P., et al.: Bioorgan. Med. Chem., 12, 3451-3469 (2004); Ohta, C. et al.: J. Org. Chem., 74, 8298 (2009); Skuballa, W. et al.: Angew. Chem., 93, 1080 (1981);