产品编号：B201930

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	B201930
名称:	N-(1H-Benzimidazol-2-ylmethyl)-N-[(8S)-5,6,7,8-tetrahydro-8-quinolinyl]-1,4-butanediamine
别名:	N1-(1H-Benzimidazol-2-ylmethyl)-N1-[(8S)-5,6,7,8-tetrahydro-8-quinolinyl]-1,4-butanediamine; AMD 070; AMD 11070; N'-(1H-Benzimidazol-2-ylmethyl)-N'-((S)-5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine;
CAS号:	558447-26-0
分子式:	C₂₁H₂₇N₅
分子量:	349.47
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	N-(1H-Benzimidazol-2-ylmethyl)-N-[(8S)-5,6,7,8-tetrahydro-8-quinolinyl]-1,4-butanediamine is a potent CXCR4 inhibitor that inhibits X4 HIV-1 replication and the gp120/CXCR4 interaction. It also has therapeutic potential for developing treatments for B-RAF wild-type and mutated melanomas.
文献	Chow, L. N., et al.: PLoS One 11, e0151765/1 (2016); O'Boyle, G., et al.: Br J Cancer. 108, 1634 (2013); Mosi, R. M., et al.: Biochem Pharmacol. 83, 472 (2012)