产品编号：B200060

产品规格：50mg

产品价格：面议

---

产品详情

标准品编号:	B200060
名称:	(S)-1,4-Benzodioxan-2-carboxypiperazine
别名:	[(2S)-2,3-Dihydro-1,4-benzodioxin-2-yl]-1-piperazinyl-methanone
CAS号:	401941-54-6
分子式:	C₁₃H₁₆N₂O₃
外观：	白色固体
熔点:	129-132ºC
分子量:	248.28
储存:	冰箱保存
溶解度:	Chloroform (Slightly), Methanol (Slightly)
类别:	Standards; Chiral Molecules;
应用:	(S)-1,4-Benzodioxan-2-carboxypiperazine is the key chiral intermediate for the synthesis of (S)-doxazosin (D537500, Mesylate salt), a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.
文献	Fang, Q., et al.: Tetrahedron Asym., 12, 2169 (2001); Elliott, H.L., et al.: Brit. J. Clin. Pharmacol., 13, 699 (1982); de Leeuw, P.W., et al.: Eur. J. Clin. Pharmacol., 23, 397 (1982)