产品编号：B197005
产品规格：5mg
产品价格：面议
| 标准品编号: | B197005 |
| 名称: | cis-4-[[2-(1H-Benzimidazol-6-ylamino)-8-quinazolinyl]oxy]-cyclohexanol |
| 别名: | NCB-​0846 |
| CAS号: | 1792999-26-8 |
| 分子式: | C₂₁H₂₁N₅O₂ |
| 外观： | 白色至淡黄色固体 |
| 分子量: | 375.42 |
| 储存: | -20°C Freezer |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 类别: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | cis-4-​[[2-​(1H-​Benzimidazol-​6-​ylamino)​-​8-​quinazolinyl]​oxy]​-​cyclohexanol inhibits Traf2 and Nck-interacting protein kinase (TNIK). TNIK is involved with Canonical Wnt/b-catenin signalling, which has regulatory roles in maintaining intestinal stem cells and aberration in this pathway has been implicated in colorectal carcinogenesis. TNIK is a therapeutic target. |
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