产品编号：B119072
产品规格：2.5mg
产品价格：面议
| 标准品编号: | B119072 |
| 名称: | BAY 87-2243-d8 |
| 别名: | 1-Cyclopropyl-4-[4-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-pyrazol-1-yl]methyl]-2-pyridinyl]-piperazine-d8 |
| 备用CAS: | 未标记：1227158-85-1 |
| 分子式: | C₂₆H₁₈D₈F₃N₇O₂ |
| 分子量: | 533.57 |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Isotope labelled BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation. It is found to inhibit HIF-1α and HIF-2α protein accumulation under hypoxic conditions in non-small cell lung cancer cell line H460. It inhibits mitochondrial complex I activity and therefore may be used in antitumor treatment to overcome chemo- and radiotherapy- resistance of hypoxic tumors. |
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