产品编号：B118660
产品规格：5mg
产品价格：面议
| 标准品编号: | B118660 |
| 名称: | Bardoxolone |
| 别名: | CDDO; RTA 401; 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid; |
| CAS号: | 218600-44-3 |
| 分子式: | C₃₁H₄₁O₄ |
| 外观： | Light Brown Solid |
| 熔点: | >280ºC (dec.) |
| 分子量: | 491.66 |
| 储存: | -20ËšC Freezer |
| 溶解度: | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| 类别: | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Bardoxolone is a synthetic oleanane triterpenoid that exerts multifunctional activities in the control of cellular growth and differentiation. Bardoxolone is capable of activating the transcription factor peroxisome proliferator activator receptor-γ (PPARγ), its apoptotic effects in malignant cells have been shown to occur independently of PPARγ. Bardoxolone was developed as an potential drug for the improvement of hyperglycemia, proteinuria, glomerulus structure, serum creatine, which may in turn be beneficial to treat diabetic kidney diseases, cancer and thromboembolic events. |
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