产品编号：A808110

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	A808110
名称:	AZD1152-HQPA
别名:	5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-Pyrazole-3-acetamide; AZD 1152HQPA; INH 34; Barasertib;AZD1152-Hydroxyquinazoline Pyrazol Anilide;
CAS号:	722544-51-6
分子式:	C₂₆H₃₀FN₇O₃
分子量:	507.56
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	AZD1152-HQPA is a a highly selective inhibitor of aurora-B kinase. AZD1152-HQPA has been shown to inhibit osteosarcoma cell line U2-OS cells proliferation. AZD1152-HQPA was also shown to be an effective apoptosis-inducing agent in acute myeloid leukemia cell lines and primary acute myeloid leukemia cultures.
文献	Liu, Z.-L. et al.: Nanch. Dax. Xueb. Yix., 50, 30 (2010); Walsby, E. et al.: Haematologica, 93, 662 (2008);