产品编号：A793930

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	A793930
名称:	Atrasentan Hydrochloride
别名:	(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic Acid Hydrochloride; [2R-(2α,3β,4α)]-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic Acid Monohydrochloride; A 147627.1; Abbott 147627;
CAS号:	195733-43-8
备用CAS:	173937-91-2-free acid
分子式:	C₂₉H₃₉ClN₂O₆
分子量:	547.08
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Atrasentan, a selective antagonist of the endothelin-A (ETA) receptor, binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.
文献	Bax, W., et al.: Trends Pharmacol. Sci., 15, 379 (1994); Winn, M., et al.: J. Med. Chem., 39, 1039 (1996); Wu-Wong, J., et al.: J. Pharmacol. Exp. Ther., 281, 791 (1997);

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