产品编号：A793925

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	A793925
名称:	Atrasentan
别名:	Altrasentan; (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic Acid; (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic Acid; (+)-A 127722; A 147627; ABT 627;
CAS号:	173937-91-2
备用CAS:	HCl Salt: 195733-43-8
分子式:	C₂₉H₃₈N₂O₆
外观:	白色固体
熔点:	121-126ºC
分子量:	510.62
储存:	-20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Atrasentan is a selective antagonist of the endothelin-A (ETA) receptor and binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.
文献	Bax, W., et al.: Trends Pharmacol. Sci., 15, 379 (1994); Winn, M., et al.: J. Med. Chem., 39, 1039 (1996); Wu-Wong, J., et al.: J. Pharmacol. Exp. Ther., 281, 791 (1997);