产品编号：A790034

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	A790034
名称:	Astemizole-d5
别名:	1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine-d5; Astemisan-d5; Hismanal-d5; Histamen-d5; Paralergin-d5; R 42512-d5; R 43512-d5; Retolen-d5; Waruzol-d5;
备用CAS:	Unlabeled: 68844-77-9
分子式:	C₂₈H₂₆D₅FN₄O
分子量:	463.6
类别:	Standards; Isotopic Labeled Analogues;
应用:	Astemizole-d5 is the deuterated form of Astemizole (A790030), which is a nonsedating-type histamine H1-receptor antagonist. Potential for combination therapy with antivancer drugs such as doxorubicin in resistant leukemia. Antihistaminic;Also, it is an intermediate used in the synthesis of O-Desmethyl Astemizole-d5 (D290752).
文献	Wauquier, A., et al.: Eur. J. Pharmacol., 72, 245 (1981), Laduron, P.M., et al.: Mol. Pharmacol., 21, 294 (1982), Richards, D.M., et al.: Drugs, 28, 38 (1984), Al-Obaid, A.M., et al.: Anal. Profiles Drug Subs., 20, 173 (1991), Ishikawa, M., et al.: Biol. Pharm. Bull., 23, 112 (2000)