产品编号：A779985

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	A779985
名称:	AS 2444697
别名:	N-[3-(Aminocarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide Hydrochloride; N-[3-Carbamoyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methylpyridin-4-yl)-1,3-oxazole-4-carboxamide Hydrochloride;
CAS号:	1287665-60-4
分子式:	C₁₉H₂₀N₆O₄•HCl
分子量:	396.403646
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	AS 2444697 is a selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor. It suppressed the progression of chronic renal failure via anti-inflammatory action in nephrectomized rats.
文献	Kondo, M., et al.: Naunyn Schmiedebergs Arch. Pharmacol., 387, 909 (2014);