产品编号:A771720
产品规格:100mg
产品价格:面议
| 标准品编号: | A771720 |
| 名称: | A77 1726 (E/Z) Mixture |
| 别名: | 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide; 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide; rac-Teriflunomide; USP Leflunomide Related Compound B; |
| 杂质: | Leflunomide USP Related Compound B |
| CAS号: | 108605-62-5 |
| 分子式: | C₁₂H₉F₃N₂O₂ |
| 外观: | 白色固体 |
| 熔点: | 228-230°C (dec.) |
| 分子量: | 270.21 |
| 储存: | Amber Vial, -20°C Freezer, Under inert atmosphere |
| 溶解度: | DMSO (Slightly), Methanol (Sparingly) |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | rac A77 1726 is the active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. The second Phase III study evaluating the efficacy of Genzyme’s teriflunomide therapy against relapsing forms of multiple sclerosis found the once-daily oral drug to be no less effective thanÂinjectable interferon beta 1a (Rebif®). Leflunomide USP Related Compound B. |
| 危险品信息: | Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package |
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