A77 1726 (E/Z) Mixture

我要购买

产品编号:A771720

产品规格:100mg

产品价格:面议


产品详情

标准品编号: A771720
名称: A77 1726 (E/Z) Mixture
别名: 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide; 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide; rac-Teriflunomide; USP Leflunomide Related Compound B;
杂质: Leflunomide USP Related Compound B
CAS号: 108605-62-5
分子式: C₁₂H₉F₃N₂O₂
外观: 白色固体
熔点: 228-230°C (dec.)
分子量: 270.21
储存: Amber Vial, -20°C Freezer, Under inert atmosphere
溶解度: DMSO (Slightly), Methanol (Sparingly)
类别: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: rac A77 1726 is the active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. The second Phase III study evaluating the efficacy of Genzyme’s teriflunomide therapy against relapsing forms of multiple sclerosis found the once-daily oral drug to be no less effective thanÂinjectable interferon beta 1a (Rebif®). Leflunomide USP Related Compound B.
危险品信息: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
文献