产品编号：A630750

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	A630750
名称:	(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid Hydrochloride
别名:	(βR)-β-Amino-2,4,5-trifluorobenzenebutanoic Acid Hydrochloride
CAS号:	1204818-19-8
备用CAS:	Free base: 936630-57-8
分子式:	C₁₀H₁₁ClF₃NO₂
状态：	白色固体
熔点：	196-201°C
分子量:	269.65
储存：	Hygroscopic, 冰箱保存, under inert atmosphere
溶解性:	DMSO (Slightly), Methanol (Slightly)
类别:	Building Blocks; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid Hydrochloride is an intermediate in the synthesis of the new antidiabetic drug Sitagliptine (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor.
参考:	Tasnadi, G., et al.: Org. Biomol. Chem., 8, 793 (2010); Kim, D., et al.: J. Med. Chem. 48, 141 (2005); Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005); Bergman, A., et al: Clin. Ther. 28, 55 (2006)

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