产品编号：A629153

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	A629153
名称:	6'-[(6-Amino-4-pyrimidinyl)amino]-8'-methylspiro[cyclohexane-1,3'(2'H)-imidazo[1,5-a]pyridine]-1',5'-dione
别名:	eFT508
CAS号:	1849590-01-7
分子式:	C₁₇H₂₀N₆O₂
状态：	淡黄色固体
熔点：	>300°C
分子量:	340.38
储存：	冰箱保存, under inert atmosphere
溶解性:	DMSO (Slightly, Heated), Methanol (Very Slightly)
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	6'-[(6-Amino-4-pyrimidinyl)amino]-8'-methylspiro[cyclohexane-1,3'(2'H)-imidazo[1,5-a]pyridine]-1',5'-dione was used in the study of inhibitors of immune checkpoint modulators and related methods. eFT508 is a potent, highly selective, and orally bioavailable MNK1 and MNK2 inhibitor.
参考:	Webster, K., et al.: U.S. Pat. Appl. Publ. (2016), US 20160303124 A1 20161020; Webster, K., et al.: Blood, 126, 1554 (2015);