产品编号:A628850
产品规格:100mg
产品价格:面议
| 标准品编号: | A628850 |
| 名称: | Aminopterin |
| 别名: | N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid; 4-Aminofolic Acid, 4-Aminopteroyl-L-glutamic Acid, 4-Amino-PGA; NSC 739; USP Methotrexate Related Compound B; Methotrexate EP Impurity B |
| 杂质: | Methotrexate EP Impurity B |
| CAS号: | 54-62-6 |
| 分子式: | C₁₉H₂₀N₈O₅ |
| 状态: | Dark Yellow Solid |
| 熔点: | >200°C (dec.) |
| 分子量: | 440.41 |
| 储存: | -20°C Freezer |
| 溶解性: | DMF, DMSO |
| 类别: | Standards; Amino Acids; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Aminopterin (Methotrexate EP Impurity B) is a folic acid antagonist. Its actively transported into cells by thefolate transporter. In the cell, its converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate reductase and inhibits its activity. |
| 危险品信息: | Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package |
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