Aminopterin

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产品编号:A628850

产品规格:100mg

产品价格:面议


产品详情

标准品编号: A628850
名称: Aminopterin
别名: N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid; 4-Aminofolic Acid, 4-Aminopteroyl-L-glutamic Acid, 4-Amino-PGA; NSC 739; USP Methotrexate Related Compound B; Methotrexate EP Impurity B
杂质: Methotrexate EP Impurity B
CAS号: 54-62-6
分子式: C₁₉H₂₀N₈O₅
状态: Dark Yellow Solid
熔点: >200°C (dec.)
分子量: 440.41
储存: -20°C Freezer
溶解性: DMF, DMSO
类别: Standards; Amino Acids; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: Aminopterin (Methotrexate EP Impurity B) is a folic acid antagonist. Its actively transported into cells by thefolate transporter. In the cell, its converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate reductase and inhibits its activity.
危险品信息: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
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