产品编号：A628755

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	A628755
名称:	2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
别名:	2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone; (S)-1-(5-Fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propan-1-amine; (S)-2-(1-Aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;
CAS号:	870281-86-0
分子式:	C₁₇H₁₆FN₃O
状态：	白色固体
熔点：	166-169ºC
分子量:	297.33
储存：	Hygroscopic, 冰箱保存, under inert atmosphere
溶解性:	Chloroform (Slightly), DMSO (Slightly), Ethanol (Sparingly)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone is used as reagent/reactant in synthetic preparation of idelalisib using the HMDS/I2-catalyzed cyclocondensation and Boc deprotection of an (aminobutyrylamino)benzamide to a nonracemic quinazoline as the key step.
参考:	Liu, J., et al.: Org. Prep. Proced. Int., 48, 337-341 (2016);