产品编号：A628745

产品规格：5g

产品价格：面议

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产品详情

标准品编号:	A628745
名称:	5-Amino-4-pyrazolecarboxamide
别名:	3-Amino-1H-pyrazole-4-carboxamide; 3-Amino-4-carbamoylpyrazole; 3-Amino-4-pyrazolecarboxamide; NSC 1402; Allopurinol EP Impurity A
杂质:	Allopurinol EP Impurity A
CAS号:	5334-31-6
分子式:	C₄H₆N₄O
状态：	灰白色至浅褐色固体
熔点：	180-185°C
分子量:	126.12
储存：	冰箱保存
溶解性:	DMSO (Slightly), Methanol (Very Slightly)
类别:	Building Blocks; Miscellaneous;
应用:	5-Amino-4-pyrazolecarboxamide is used in the synthesis of 4H-3,1-Benzothiazinone analogs as antiproliferative agents against human cancer cell lines. Also, it is an intermediate used in the synthesis of 3-(4H-1,2,4-Triazol-4-yl)-1H-pyrazole-4-carboxamide (T767570), which is an impurity of Allopurinol (A547300), which is a xanthine oxidase inhibitor; decreases uric acid production. Used in treatment of hyperuricemia and chronic gout. Antiurolithic.
参考:	Matysiak, J., et al.: Arab. J. Chem., (2015); Benezra, S.A., et al.: Anal. Profiles Drug Subs., 7, 1, (1978); Dalbeth, N., et al.: Rheumatology, 44, 1090 (2005); Dinarello, C., et al.: J. Exp. Med., 201, 1355 (2005);