产品编号：A619175

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	A619175
名称:	(2R,3R,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl Benzoate
分子式:	C₂₄H₂₂FN₃O₆
状态：	白色固体
分子量:	467.45
储存：	0-5 °C Fridge
溶解性:	DMSO, Methanol
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
应用:	(2R,3R,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl Benzoate is an intermediate in synthesizing PSI 6130 (P839680), which is an experimental treatment for hepatitis C. PSI 6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI 6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B.
参考:	Clark, J., et al.: J. Med. Chem., 48, 5504 (2005); Stuyver, L., et al.: Antiviral Chem. Chem., 17, 79 (2006)