产品编号：A614130

产品规格：2mg

产品价格：面议

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产品详情

标准品编号:	A614130
名称:	3-[4-(Aminomethyl)benzyloxy] Thalidomide SF-1-088
分子式:	C₅₃H₅₅N₅O₁₀S
分子量:	954.1
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-[4-(Aminomethyl)benzyloxy] Thalidomide SF-1-088 is a potential small molecule inhibitor of Stat3 and Stat5-SH2 domain. Useful in the treatment of human cancers. Antileukemia agent. Derivative of Thalidomide (T338850), Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.
参考:	D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)