产品编号：A612560

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	A612560
名称:	N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine
别名:	GS 7160; Tenofovir Impurity;
CAS号:	376633-24-8
分子式:	C₁₂H₁₉N₆O₅P
分子量:	358.29
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine is a metabolite of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral.
参考:	Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);