产品编号：A609725

产品规格：1g

产品价格：面议

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产品详情

标准品编号:	A609725
名称:	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
别名:	4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide;4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic Acid Methylamide
CAS号:	757251-39-1
分子式:	C₁₃H₁₂FN₃O₂
状态：	Orange to Dark Red to Brown Solid
熔点：	135 - 137°C
分子量:	261.25
储存：	Room Temperature, under inert atmosphere
溶解性:	Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly)
类别:	Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer.
参考:	Mross, K., et al.: Clin. Cancer Res., 18, 2658 (2012); Stiehl, J., et al. Process for Preparation of Regorafenib. PCT Int. Appl. 2011128261. Oct 20, 2011; Van Cutsem, E., et al.: J. Clin. Oncol., 30, 3502 (2012)