产品编号：A605115

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	A605115
名称:	(±)-4-Amino-3-(3,4-dimethoxyphenyl)-1-methyl-piperidine
别名:	3-(3,4-dimethoxyphenyl)-1-methyl-4-piperidinamine
CAS号:	24218-09-5
分子式:	C₁₄H₂₂N₂O₂
状态：	Semi-Solid (Brown)
分子量:	250.34
溶解性:	Dichloromethane, Ether, Ethyl Acetate, Methanol
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(±)-4-Amino-3-(3,4-dimethoxyphenyl)-1-methyl-piperidine is an intermediate in the synthesis of Tolafentrine (T531000), which is a dual-selective phosphodiesterase 3/4 inhibitor used in chronic experimental pulmonary hypertension.
参考:	Huxtable, R., et al.: Pharmacol. Ther., 47, 371 (1990), Tanaka, K., et al.: Cancer Res., 55, 2927 (1995), Wagner, R., et al.: J. Pharmacol. Exp. Ther., 282, 1650 (1997), Cowan, K., et al.: Nat. Med., 6, 698 (2000), Shankavaram, U., et al.: J. Biol. Chem., 276, 19027 (2001),