产品编号：A602760

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	A602760
名称:	N-(Aminocarbonyl)-3-methoxy-O,α-dimethyl-L-tyrosine
别名:	L-4-(3,4-Dimethoxybenzyl)-4-methylhydantoic Acid; L-α-(3,4-Dimethoxybenzyl)-α-methylhydantoic Acid; L-α-Methyl-α-ureido-β-(3,4-dimethoxyphenyl)propionic Acid; L-N-Carbamoyl-3-(3,4-dimethoxyphenyl)-2-methyl-alanine;
CAS号:	28861-00-9
分子式:	C₁₃H₁₈N₂O₅
分子量:	282.29
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-(Aminocarbonyl)-3-methoxy-O,α-dimethyl-L-tyrosine is an intermediate used in the synthesis of (S)-(-)-Carbidopa (C175985), which is a peripheral decarboxylase inhibitor that is commonly used in combination with L-DOPA (D533751) for treatment of Parkinsonism. S(-)-Carbidopa ( has also been shown to prolong the elimination half-life of L-DOPA from blood plasma and skeletal muscle.
参考:	Henry, G.M. et al.: Psychosom. Med., 38, 95 (1976); Leguire, L.E. et al.: Invest. Ophthalmol. Vis. Sci. 34, 3090 (1993); Deleu, D. et al.: Naun. Schmied. Arch. Pharmacol. 348: 576 (1993);