产品编号：A602050

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	A602050
名称:	3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
别名:	INK 128; MLN 0128; Sapanisertib
CAS号:	1224844-38-5
分子式:	C₁₅H₁₅N₇O
状态：	白色至白色固体
熔点：	270-272°C (dec.)
分子量:	309.33
储存：	Hygroscopic, 冰箱保存, under inert atmosphere
溶解性:	DMSO (Slightly), Methanol (Slightly)
稳定性:	Hygroscopic
类别:	Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a potent and selective TORC1/2 inhibitor with broad oral antitumor activity. TORC1/2 inhibitors are mechanistically distinct from rapamycinand offer a compelling approach to the treatment of cancer by targeting translational control, cell metabolism, growth andangiogenesis.
参考:	Katayoun, J., et al.: Molec. Cancer. Therap., 8, 1158 (2009);