产品编号：A601630

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	A601630
名称:	N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester
CAS号:	1013330-79-4
分子式:	C₂₂H₂₁N₃O₃
状态：	白色固体
熔点：	172-174°C
分子量:	375.42
储存：	冰箱保存
溶解性:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester is a biaryl benzamides that exhibit inhibitory selectivity over class II Histone Deacetylase (HDACs) and as well as class I HDACs. N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester was deteremined to be a potent and selective inhibitor of HDAC with reduced off-target activity and tumor growth inhibition activity.
参考:	Witter, D.J., et al.: Bioorg. Medn. Chem. Letters., 18, 726 (2008);