产品编号：A601545

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	A601545
名称:	(γS)-γ-Amino-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid Ethyl Ester Hydrochloride
别名:	(4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate Hydrochloride
CAS号:	2055844-49-8
备用CAS:	Free Base: 2055844-47-6
分子式:	C₂₀H₂₅NO₂ • (HCl)
状态：	白色固体
分子量:	311.423646
溶解性:	Dichloromethane, Ethyl Acetate
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines;
应用:	(γS)-γ-Amino-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid Ethyl Ester Hydrochloride is an intermediate in the synthesis of (2S,4R)-Sacubitril (S080905). (2S,4R)-Sacubitril is the enantiomer and an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.
参考:	McMurray, J., et al.: N. Eng. J. Med., 371 (2014)