产品编号：A576555

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	A576555
名称:	4-[4-[(Butylamino)carbonyl]-2-[[(2,4-dichlorophenyl)sulfonyl]amino]phenoxy]-3-methoxy-benzeneacetic Acid
CAS号:	1027847-67-1
分子式:	C₂₆H₂₆Cl₂N₂O₇S
分子量:	581.46
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	4-[4-[(Butylamino)carbonyl]-2-[[(2,4-dichlorophenyl)sulfonyl]amino]phenoxy]-3-methoxy-benzeneacetic Acid is a dualÂprostanoid D receptorÂ(DP) andÂchemoattractant receptor-homologous molecule expressed on Th2 cellsÂ(CRTH2) antagonist. DP and CRTH2 are involved in mediating allergic reactions (asthma, allergic rhinitis, and atopic dermatitis). Compounds that inhibit these receptors may hold potential for treating allergic diseases.
参考:	Liu, J., et al.: Bioorg. Med. Chem. Lett.Â19, 6419 (2009); Liu, J., et al.:ÂACS Med Chem Lett. 2, 326 (2011)