产品编号：A549650
产品规格：1mg
产品价格：面议
| 标准品编号: | A549650 |
| 名称: | 17-(Allylamino) Geldanamycin |
| 别名: | 17-Demethoxy-17-(2-propenylamino)geldanamycin; 17-(Allylamino)-17-demethoxygeldanamycin; 17-(Allylamino)-17-desmethylgeldanamycin; 17-Demethoxy-17-allylaminogeldanamycin; 17AAG; CP 127374; KOS 953; NSC 330507; Tanespimycin; 17-AAG |
| CAS号: | 75747-14-7 |
| 分子式: | C₃₁H₄₃N₃O₈ |
| 状态： | Dark Purple to Very Dark Red Solid |
| 熔点： | >194°C (dec.) |
| 分子量: | 585.69 |
| 储存： | -20°C Freezer, Under Inert Atmosphere |
| 溶解性: | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. |
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