Agmatine Sulfate

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产品编号:A426900

产品规格:250mg

产品价格:面议


产品详情

标准品编号: A426900
名称: Agmatine Sulfate
别名: N-(4-aminobutyl)guanidine Sulfate; NIH 11035
CAS号: 2482-00-0
备用CAS: Free Base: 306-60-5
分子式: C₅H₁₆N₄O₄S
状态: 白色至白色固体
熔点: 231-233°C
分子量: 228.27
储存: Room Temp
溶解性: Water (Slightly, Heated)
类别: Standards; Amino Acids; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;
应用: General Uses: Neuroprotective, CNS studies, Autism and depression research Description: Agmatine Sulfate is a polyamine derived from L-arginine (A769500) decarboxylation and is a known putative endogenous neurotransmitter at imidazoline receptors. Agmatine sulfate displaces clonidine at α2-adrenergic and at imidazoline receptors and was recently shown to exert some neuroprotective effects. It blocks NMDVIP(LA)receptor associated cation channels. Acts as a competitive inhibitor of nitric oxide synthase (NOS). It functions as neurotransmitter since it is stored in synaptic vesicles and is related from axon terminals by depolarization(1). Protects autistic behavior in rats (2) and reverses depressive like behavior in mice. (3)
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