产品编号:A426900
产品规格:250mg
产品价格:面议
| 标准品编号: | A426900 |
| 名称: | Agmatine Sulfate |
| 别名: | N-(4-aminobutyl)guanidine Sulfate; NIH 11035 |
| CAS号: | 2482-00-0 |
| 备用CAS: | Free Base: 306-60-5 |
| 分子式: | C₅H₁₆N₄O₄S |
| 状态: | 白色至白色固体 |
| 熔点: | 231-233°C |
| 分子量: | 228.27 |
| 储存: | Room Temp |
| 溶解性: | Water (Slightly, Heated) |
| 类别: | Standards; Amino Acids; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | General Uses: Neuroprotective, CNS studies, Autism and depression researchDescription:Agmatine Sulfate is a polyamine derived from L-arginine (A769500) decarboxylation and is a known putative endogenous neurotransmitter at imidazoline receptors. Agmatine sulfate displaces clonidine at α2-adrenergic and at imidazoline receptors and was recently shown to exert some neuroprotective effects. It blocks NMDVIP(LA)receptor associated cation channels. Acts as a competitive inhibitor of nitric oxide synthase (NOS). It functions as neurotransmitter since it is stored in synaptic vesicles and is related from axon terminals by depolarization(1). Protects autistic behavior in rats (2) and reverses depressive like behavior in mice. (3) |
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