Apigenin 5-O-β-D-Glucuronide

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产品编号:A426510

产品规格:1mg

产品价格:面议


产品详情

标准品编号: A426510
名称: Apigenin 5-O-β-D-Glucuronide
别名: (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-((7-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-5-yl)oxy)tetrahydro-2H-pyran-2-carboxylic Acid
CAS号: 952414-48-1
分子式: C₂₁H₁₈O₁₁
状态: Green Solid
分子量: 446.36
储存: Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解性: DMSO (Slightly), Methanol (Slightly)
类别: Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用: Apigenin 5-O-β-D-Glucuronide is a metabolite of Apigenin (A726500), Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap junction intracellular communication in liver cells.
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