产品编号：A325602

产品规格：

产品价格：面议

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产品详情

标准品编号:	A325602
名称:	AEE 788-d5
别名:	6-[4-[(4-(Ethyl-d5)-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine; [6-[4-[(4-(Ethyl-d5)piperazin-1-yl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-((R)-1-phenylethyl)amine; NVP-AEE 788-d5;
CAS号:	1292840-54-0
备用CAS:	497839-62-0-未标记
分子式:	C₂₇H₂₇D₅N₆
分子量:	445.61
类别:	Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Labelled AEE 788. A novel dual receptor tyrosine kinase inhibitor of the EGF and the VEGF receptor, for treatment of human HCC cell lines and in a s.c. xenograft model.
参考:	Ito, Y., et al.: Br. J. Cancer., 84, 1377 (2001), Huether, A., et al.: Biochem. Pharmacol., 70, 1568 (2005), Zhu, A., et al.: J. Clin. Oncol. 24, 1898 (2006), Fang, D., et al.: J. Biol. Chem., 282, 11221 (2007),