产品编号：A247530

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	A247530
名称:	Adefovir Dipivoxil Dimer
别名:	Adefovir Dipivoxil Impurity B; 2,2-Dimethyl-propanoic Acid Methylenebis[imino-9H-purine-6,9-diyl-2,1-ethanediyloxymethylenephosphinylidynebis(oxymethylene)] Ester
CAS号:	323201-05-4
分子式:	C₄₁H₆₄N₁₀O₁₆P₂
状态：	Clear Colorless Sticky Gel
熔点：	未标明外观
分子量:	1014.95
储存：	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解性:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Adefovir Dipivoxil Dimer is a formed from the dimerization of Adefovir Dipivoxil (A280465) which is used as an oral reverse transcriptase inhibitor in the treatment of hepatitis B. Adefovir Dipivoxil Dimer’s presence indicates the degradation of Adefovir Dipivoxil under specific conditions suggesting the stability of Adefovir Dipivoxil is compromised under such conditions.
参考:	Yuan, L., et al.: Pharm. Res., 17, 1098 (2000); Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010), Ming, X., et al.: Biochem. Pharmacol., 79, 455 (2010)

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