产品编号：A173865

产品规格：250mg

产品价格：面议

---

产品详情

标准品编号:	A173865
名称:	(3E)-1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylic Acid Methyl Ester
CAS号:	1168152-06-4
分子式:	C₂₁H₁₉NO₅
分子量:	365.38
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(3E)-1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylic Acid Methyl Ester is an impurity of Intedanib (I666650), an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases.
参考:	Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)