产品编号：A115153

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	A115153
名称:	Abemaciclib
别名:	N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine; LY 2835219; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine
CAS号:	1231929-97-7
分子式:	C₂₇H₃₂F₂N₈
状态：	淡黄色固体
熔点：	175-178°C
分子量:	506.59
储存：	-20°C Freezer
溶解性:	Chloroform (Slightly), Methanol (Slightly)
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	Abemaciclib is a potent and selective inhibitor of cyclin-dependent kinases, CDK4 and CDK6, as a method to inhibit the proliferation of cancer cells.
参考:	O'Leary, Ben., et al.: Nat Rev Clin Oncol.,13,417 (2016); Van Arsdale., et al.: Clin. Cancer Res., 21,2905(2015);

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