产品编号：A108540

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	A108540
名称:	Abiraterone N-Oxide
分子式:	C₂₄H₃₁NO₂
状态：	白色固体
熔点：	>240°C (dec.)
分子量:	365.51
储存：	Hygroscopic, 冰箱保存, under inert atmosphere
溶解性:	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
应用:	Abiraterone N-Oxide is a derivative of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
参考:	Denis, L., et al.: Cancer, 72, 3888 (1993), Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995), Denmeade, S., et al.: Nat. Rev., 2, 389(2002), Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005),

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