产品编号：A108527

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	A108527
名称:	Abiraterone Ethyl Ether-d5
别名:	3-((3S,8R,9S,10R,13S,14S)-3-ethoxy--d5-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine
备用CAS:	Unlabelled CAS# N/A
分子式:	C₂₆H₃₀D₅NO
分子量:	382.59
类别:	Building Blocks; Isotopic Labeled Analogues;
应用:	Abiraterone Ethyl Ether-d5 is the labeled analogue of Abiraterone Ethyl Ether (A108525), an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
参考:	Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)