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产品基本信息
产品编号：I666650
产品名称：Intedanib
产品CAS：656247-17-5
规格含量：25 mg
产品价格：面议
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产品详细介绍
标准品编号:
I666650
名称:
Intedanib
别名:
(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-H-Indole-6-carboxylic Acid Methyl Ester; BIBF 1120; Ofev; Vargatef; Nintedanib
CAS号:
656247-17-5
分子式:
C₃₁H₃₃N₅O₄
外观:
Light Yellow to Light Green Solid
熔点:
>237ºC (dec.)
分子量:
539.62
储存:
冰箱
溶解度:
DMSO (Slightly), Methanol (Slightly)
种类:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.
参考文献
Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)
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