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| 产品基本信息 |
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| 产品编号：T897135 |
| 产品名称：Tubulysin A |
| 产品CAS：205304-86-5 |
| 规格含量：1mg |
| 产品价格：面议 |
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| 产品详细介绍 |
| 标准品编号: |
T897135 |
| 名称: |
Tubulysin A |
| 别名: |
(αS,γR)-γ-[[[2-[(1R,3R)-1-(Acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(3-methyl-1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-α-methyl-benzenepentanoic Acid; |
| CAS号: |
205304-86-5 |
| 分子式: |
C₄₃H₆₅N₅O₁₀S |
| 分子量: |
844.07 |
| 类别: |
Standards; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics; |
| 应用: |
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins are cytotoxic peptides, which include 9 members (VIP(LA)I). Tubulysin A has potential application as an anticancer agent. It arrests cells in the G2/M phase. Tubulysin A inhibits polymerization more efficiently than vinblastine and induces depolymerization of isolated microtubules. Tubulysin A has potent cytostatic effects on various tumor cell lines with IC50 in the picomolar range. |
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