1-[[[5-(4-Chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidinedione-d8 Dihydrochloride; NE 10064-d8 Dihydrochloride
备用CAS:
149888-94-8未标记
分子式:
C₂₃H₂₂D₈Cl₃N₅O₃
外观:
淡黄色固体
熔点:
>216°C (dec.)
分子量:
538.92
储存:
Hygroscopic, 冰箱保存, under inert atmosphere
溶解度:
Methanol (Slightly, Heated), Water (Slightly)
类别:
Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Azimilide-d8 Dihydrochloride is the isotope labelled analog of Azimilide dihydrochloride. Azimilide Dihydrochloride is an oral type III potassium channel blocker agent that blocks both the rapid activating component and the slow activating component of the delayed rectifier potassium current. Both preclinical and clinical studies have demonstrated the efficacy of azimilide and its safety in the treatment of supraventricular and ventricular tachyarrhythmia. Azimilide also is being studied in a worldwide multicenter trial for prevention of sudden cardiac death in patients after myocardial infarction.
危险品信息:
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package