5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine_1363380-51-1_C371555

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产品基本信息

产品编号：C371555

产品名称：5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine

产品CAS：1363380-51-1

规格含量：500mg

产品价格：面议

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产品详细介绍

标准品编号:	C371555
名称:	5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine
CAS号:	1363380-51-1
分子式:	C₆H₃ClN₄O₂
外观:	Purple Solid
熔点:	163 - 165Â°C
分子量:	198.57
储存:	Hygroscopic, 冰箱保存, under inert atmosphere
溶解度:	Chloroform (Slightly, Heated), DMSO (Slightly)
类别:	Building Blocks; Miscellaneous;
应用:	5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine is used in the preparation of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, a tyrosine kinase (TRK) inhibitor for treating cancer.
参考文献	Reynolds, M., et al.: PCT Int. Appl. (2017), WO 2017201241 A1 20171123

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