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产品基本信息
产品编号：H950690
产品名称：N-((5-Hydroxy-6-oxo-4-((2,4,6-trifluorobenzyl)carbamoyl)-1,6-dihydropyrimidin-2-yl)methyl)
产品CAS：
规格含量：2.5mg
产品价格：面议
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产品详细介绍
标准品编号:
H950690
名称:
N-((5-Hydroxy-6-oxo-4-((2,4,6-trifluorobenzyl)carbamoyl)-1,6-dihydropyrimidin-2-yl)methyl)-1,3,4-oxadiazole-2-carboxamide
分子式:
C₁₆H₁₁F₃N₆O₅
外观:
白色至Pale Beige Solid
熔点:
>250°C (dec.)
分子量:
424.29
储存:
-20°C Freezer
溶解度:
Dichloromethane (Slightly), DMSO (Slightly)
种类:
Standards; Enzyme Activators and Inhibitors;
应用:
N-((5-Hydroxy-6-oxo-4-((2,4,6-trifluorobenzyl)carbamoyl)-1,6-dihydropyrimidin-2-yl)methyl)-1,3,4-oxadiazole-2-carboxamide is a derivative of Raltegravir (R100305), a potent integrase (IN) inhibitor for WT and S217Q PFV IN.
参考文献
Hare, S., et al.: Proc. Natl. Acad. Sci. U. S. A., 107, 20057 (2010); Hicks, C., et al.: Clin. Infect. Dis., 48, 931 (2009); Moss, D., et al.: Antimicrob. Agents Chemother., 56, 3020 (2012); Hare, S., et al.: Mol. Pharmacol., 80, 565 (2011)
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