(17α)-Estra-1,3,5(10)-triene-3,17-diol; 1,3,5-Estratriene-3,17α-diol; 13β-Methyl-1,3,5(10)-gonatriene-3,17α-diol; 17-Epiestradiol; 17α-Oestradiol; 3,17-Dihydroxyestratriene; 3,17α-Dihydroxyoestra-1,3,5(10)-triene; Alfatradiol; Epiestrol; Estra-1,3,5(10)-triene-3,17α-diol; NSC 20293; α-Estradiol; Ethinyl Estradiol Impurity L (EP); Estradiol 17α-Hydroxy Impurity Estradiol EP Impurity B
杂质:
Estradiol 17α-Hydroxy Impurity; Estradiol EP Impurity B; Ethinylestradiol EP Impurity L
CAS号:
57-91-0
分子式:
C₁₈H₂₄O₂
外观:
白色至白色固体
熔点:
210-219°C
分子量:
272.38
储存:
冰箱保存
溶解度:
Dioxane (Slightly), Methanol (Slightly)
种类:
Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain(1,2). 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke(3). This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.
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