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产品编号：D448735
产品名称：1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one Dihydrochloride
产品CAS：781649-84-1
规格含量：500mg
产品价格：面议
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产品详细介绍
标准品编号:
D448735
名称:
1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one Dihydrochloride
别名:
1-(Piperidin-4-yl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one Dihydrochloride; 1-(Piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one Dihydrochloride; 1-Piperidin-4-yl-1,3-dihydroimidazo[4,5-b]pyridin-2-one Dihydrochloride; 2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine Dihydrochloride
CAS号:
781649-84-1
参考CAS号:
Free Base: 185961-99-3
分子式:
C₁₁H₁₆Cl₂N₄O
外观:
Gray to Dark Gray Solid
熔点:
>256°C (dec.)
分子量:
291.18
储存:
Hygroscopic, 冰箱保存, under inert atmosphere
溶解性:
DMSO (Slightly), Methanol (Slightly)
种类:
Building Blocks; Miscellaneous;
应用:
1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one is an intermediate used to prepare (3R,6S)-3-amino-6-(2,3-difluorophenyl)azepan-2-one of Telcagepant (MK-0974) for use as a calcitonin gene-related peptide receptor antagonist treating migraine headaches.
参考文献
Burgey, C., et al.: Org. Lett., 10, 3235 (2008);
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